Thyroid Antibodies (TPO & Thyroglobulin)
Measures TPO and thyroglobulin antibodies to identify whether a thyroid condition such as Hashimoto’s or Graves’ disease has an autoimmune cause.
Blood Tests, Thyroid- Description
- Associated Conditions
- Uses of This Test
- Why This Test?
The Thyroid Antibodies test measures thyroid peroxidase (TPO) and thyroglobulin antibodies, the two markers used to identify autoimmune thyroid disease. When these antibodies are raised, it suggests the immune system is targeting the thyroid gland, which is the underlying cause of most thyroid disorders in the UK.
Raised antibodies are the hallmark of Hashimoto’s thyroiditis, the most common cause of an underactive thyroid, and are also often seen in Graves’ disease, a cause of an overactive thyroid. Testing antibodies is particularly helpful when your TSH or thyroid hormone levels are borderline and the cause is unclear.
This test pairs well with a thyroid hormone panel (TSH, free T4 and free T3) for a complete picture. Your clinician will interpret the antibody result alongside your symptoms and any thyroid function results.
Autoimmune Thyroid Disease
Thyroid antibodies confirm whether a thyroid problem has an autoimmune cause.
Hashimoto's Thyroiditis
Raised TPO and thyroglobulin antibodies are the classic finding in Hashimoto's thyroiditis, the most common cause of an underactive thyroid.
Graves' Disease
TPO antibodies are also commonly raised in Graves' disease, a cause of an overactive thyroid.
Unexplained Thyroid Symptoms
Helps explain thyroid symptoms when TSH and thyroid hormones are borderline.
- Investigate a suspected autoimmune thyroid condition
- Confirm Hashimoto's or Graves' disease
- Explain borderline or fluctuating thyroid results
- Assess thyroid symptoms such as fatigue or weight change
- Monitor known autoimmune thyroid disease
This test measures the two main thyroid antibodies, TPO and thyroglobulin, to find out whether a thyroid problem is being driven by the immune system. It is often the missing piece when thyroid symptoms are present but standard thyroid results are borderline or hard to interpret.
- Confirms an autoimmune cause behind an underactive or overactive thyroid
- Central to diagnosing Hashimoto’s thyroiditis and Graves’ disease
- Helps make sense of fluctuating or borderline TSH results
- Useful if you have a family history of thyroid or autoimmune conditions
What We Test
Biomarkers analysed by accredited UK laboratories
Biomarkers Tested
Thyroid Antibodies
- Thyroid Peroxidase Antibodies (TPO)
Antibodies against thyroid peroxidase, an enzyme involved in thyroid hormone production. Raised levels are the hallmark of autoimmune thyroid conditions such as Hashimoto’s thyroiditis and Graves’ disease.
- Thyroglobulin Antibodies
Antibodies against thyroglobulin, a protein made by the thyroid. Often raised alongside TPO antibodies in autoimmune thyroid disease.
Measures TPO and thyroglobulin antibodies to identify autoimmune thyroid disease.
Home Finger-Prick Testing
Enjoy the convenience of testing from home with a simple, easy-to-use kit delivered straight to your door. Your kit includes clear instructions, sterile equipment, and a prepaid return envelope for sending your sample to the laboratory.
This option is ideal if you prefer flexibility, have a busy schedule, or want to check your health privately without visiting the clinic.
Results are processed by accredited laboratories, giving you the same clinical accuracy as an in-clinic test. Expect results within 72 hours!
Why Use This Service:
Perfect for busy schedules
Results within 72 hours
Delivery across the UK
Private & discreet
Avoid travelling to Preston
Cost effective alternative
Taking Charge Of Your Own Health Has Never Been Easier
Worried about your wellbeing?
If you’re experiencing unexplained symptoms such as fatigue, weight loss, or other issues, a comprehensive blood test may be the key to discovering potential underlying health problems.
Need to monitor a health condition?
Blood tests offer essential insights into various aspects of your health, from detecting deficiencies to evaluating immune functions.
Enhancing Performance and Fitness?
Whether you’re training for a sport or keeping track of your fitness progress, a blood test serves as an excellent foundation for your performance improvement journey.
All Our Tests Include:
No GP Referral
Order directly - no waiting for appointments
Fast Results
Detailed analysis within 72 hours
Laboratory Commentary
Expert interpretation of your results included
Secure & Confidential
Discreet service and consultations
Frequently Asked Questions
- Qualified Pharmacists
- Flexible Appointments
- Top Customer Service
What if my results need explaining?
Every result comes with a doctor’s commentary written in plain English, so you understand what your numbers mean. If anything is unclear or needs a follow-up, our pharmacists are happy to talk you through it.
How much do private blood tests cost in Preston?
Prices start at £39 for a single-marker test such as our Cholesterol/Lipid Profile and rise to £349 for the Allergy Complete 295-allergen panel. Most comprehensive health panels cost between £100 and £180, and every result includes a doctor’s commentary at no extra charge.
What is the difference between a home finger-prick test and a clinic appointment?
Both use exactly the same accredited UK laboratories. A home kit suits busy schedules and simpler tests, while a clinic appointment with our phlebotomist is better for comprehensive panels, larger samples, or anyone who would rather not take their own sample. If you are not sure which to choose, call us and we will point you to the right option.
Where is the clinic?
You will find us at 54 Berry Lane, Longridge, Preston PR3 3JP, with free parking on site. We see patients from Longridge, Preston, the Ribble Valley and across Lancashire.
Are weekend appointments available?
Yes. We are open 10am to 6pm on Saturdays, with blood test appointments available by arrangement, so you can fit your test around work and family.
Are same-day appointments available?
Often, yes. If you need a blood test today, call us on 01772 439054 and we will do our best to fit you in the same day.
What if I’m on the pill, coil or HRT?
Just tell us at booking. Hormonal contraception and HRT affect some results, and our commentary will interpret your numbers in that context so they actually make sense for you.
What can an AMH test tell me?
AMH is the single best blood marker of your ovarian reserve, a useful indicator if you’re planning for a family, considering egg freezing, or simply want to understand your fertility. It can be tested on any day of your cycle.
When in my cycle should I take a hormone test?
It depends on the test. AMH can be done on any day. Baseline hormones (FSH, LH, oestradiol) are usually taken on days 2 to 5. Progesterone is taken around day 21 (about 7 days before your next period is due). We’ll guide you on timing when you book.
When is the best time to take a testosterone test?
Ideally in the morning (before 11am), when testosterone is at its natural peak. We’ll guide you on timing when you book.
What’s the best test if I think my testosterone is low?
Testosterone Plus, which measures total and free testosterone plus SHBG and the Free Androgen Index. Total testosterone alone misses many men whose symptoms come from low free testosterone, so getting the complete picture matters.
Do I need an allergy test or intolerance test?
If your reactions are fast (hives, swelling, wheezing), the 295-allergen IgE panel is the right starting point. If they’re slower and gut-based (bloating, cramps, fatigue), a targeted intolerance or coeliac profile may suit you better. Not sure? Call us and we’ll guide you.
What does the 295-allergen panel test for?
Foods, pollens, animals, dust mites, moulds, insect venoms, drugs and contact allergens (all from a single blood sample). The full allergen list can be found on the product page.
How accurate are home finger-prick tests compared to clinic tests?
Our home finger-prick tests use the same accredited laboratories as our clinic tests. While clinic tests allow for more comprehensive panels, home tests are highly accurate for the parameters they measure.
Do I need a GP referral for a blood test?
No, you don’t need a GP referral. You can book directly with us for any blood test. We are a private clinic offering direct access to comprehensive blood testing.
How old do I have to be to have a blood test?
We will only draw blood from those aged 16 and above due to legal requirements.
How long does it take for the blood test results to come?
If you have used our clinic to complete a blood test, we send off all samples the same day to the lab to be processed. If you have used a home test kit, then once your sample has been sent off the lab will analyse your sample. Results are usually received within 72 hours.
How do I perform the home finger-prick test?
Your home blood test kit will contain easy-to-follow instructions on how to take your own finger blood sample. If you have any concerns or questions prior to using the kit, please contact our phlebotomists who will be happy to assist.
How do I prepare for a blood test?
There is no preparation required prior to taking any of the blood tests. Please simply remember to stay hydrated prior to your appointment. This is to help your veins dilate better to enable a quick and efficient blood sample to be taken and reduce the risks of feeling faint following your blood test.
Please inform the phlebotomist before your test if you are currently taking any blood thinning medication.
Should I fast before my blood test?
Fasting is not required for most blood tests. However, if your profile includes cholesterol tests and you’ve previously had high levels, consider fasting for 8 hours beforehand. While not essential, fasting can provide more accurate results.
Note: Fasting means abstaining from any food and drink, except for water.