Sex Hormone Binding Globulin (SHBG)
An essential hormone-carrier test that improves the interpretation of testosterone and oestradiol results, useful in TRT, HRT, PCOS and insulin resistance.
Blood Tests, Female Health, General Health, Male Health- Description
- Associated Conditions
- Uses of This Test
- Why This Test?
SHBG is the protein that binds and transports testosterone and oestradiol in the blood. Levels affect how much hormone is biologically available to tissues, making SHBG essential for interpreting total testosterone and oestradiol results accurately.
Low SHBG is commonly seen in PCOS and metabolic syndrome, while high SHBG can mask functional androgen deficiency in men.
Hormone Binding Capacity
SHBG affects how much hormone is biologically available; both high and low values are clinically relevant.
PCOS Investigation
Low SHBG is common in PCOS and is linked to insulin resistance.
TRT/HRT Monitoring
Important for accurate interpretation of total testosterone and oestradiol on TRT or HRT.
- Interpret total testosterone or oestradiol results
- Investigate low testosterone or PCOS
- Monitor TRT or HRT
- Investigate insulin resistance
Sex Hormone Binding Globulin (SHBG) is the protein that binds testosterone, oestradiol and DHT in the blood. When SHBG is high, less hormone is available to tissues; when SHBG is low, more is available, but this is often associated with insulin resistance and metabolic disease.
SHBG testing helps interpret total testosterone or oestradiol results and is particularly useful in:
- Men investigating symptoms of low testosterone
- Women with PCOS, irregular cycles or excess hair growth
- Patients on TRT or HRT requiring complete hormonal assessment
- Investigating insulin resistance and metabolic syndrome
What We Test
Biomarkers analysed by accredited UK laboratories
Biomarker Tested
Hormone Carrier Protein
- Sex Hormone Binding Globulin (SHBG)
The carrier protein for testosterone and oestradiol. Determines how much hormone is biologically active. Low SHBG is associated with insulin resistance.
Measures Sex Hormone Binding Globulin, which binds testosterone and oestradiol in the blood.
Home Finger-Prick Testing
Enjoy the convenience of testing from home with a simple, easy-to-use kit delivered straight to your door. Your kit includes clear instructions, sterile equipment, and a prepaid return envelope for sending your sample to the laboratory.
This option is ideal if you prefer flexibility, have a busy schedule, or want to check your health privately without visiting the clinic.
Results are processed by accredited laboratories, giving you the same clinical accuracy as an in-clinic test. Expect results within 72 hours!
Why Use This Service:
Perfect for busy schedules
Results within 72 hours
Delivery across the UK
Private & discreet
Avoid travelling to Preston
Cost effective alternative
Taking Charge Of Your Own Health Has Never Been Easier
Worried about your wellbeing?
If you’re experiencing unexplained symptoms such as fatigue, weight loss, or other issues, a comprehensive blood test may be the key to discovering potential underlying health problems.
Need to monitor a health condition?
Blood tests offer essential insights into various aspects of your health, from detecting deficiencies to evaluating immune functions.
Enhancing Performance and Fitness?
Whether you’re training for a sport or keeping track of your fitness progress, a blood test serves as an excellent foundation for your performance improvement journey.
All Our Tests Include:
No GP Referral
Order directly - no waiting for appointments
Fast Results
Detailed analysis within 72 hours
Laboratory Commentary
Expert interpretation of your results included
Secure & Confidential
Discreet service and consultations
Frequently Asked Questions
- Qualified Pharmacists
- Flexible Appointments
- Top Customer Service
What is the difference between a home finger-prick test and a clinic appointment?
Both use exactly the same accredited UK laboratories. A home kit suits busy schedules and simpler tests, while a clinic appointment with our phlebotomist is better for comprehensive panels, larger samples, or anyone who would rather not take their own sample. If you are not sure which to choose, call us and we will point you to the right option.
Where is the clinic?
You will find us at 54 Berry Lane, Longridge, Preston PR3 3JP, with free parking on site. We see patients from Longridge, Preston, the Ribble Valley and across Lancashire.
Are weekend appointments available?
Yes. We are open 10am to 6pm on Saturdays, with blood test appointments available by arrangement, so you can fit your test around work and family.
Are same-day appointments available?
Often, yes. If you need a blood test today, call us on 01772 439054 and we will do our best to fit you in the same day.
What if my results need explaining?
Every result comes with a doctor’s commentary written in plain English, so you understand what your numbers mean. If anything is unclear or needs a follow-up, our pharmacists are happy to talk you through it.
How much do private blood tests cost in Preston?
Prices start at £39 for a single-marker test such as our Cholesterol/Lipid Profile and rise to £349 for the Allergy Complete 295-allergen panel. Most comprehensive health panels cost between £100 and £180, and every result includes a doctor’s commentary at no extra charge.
What if I’m on the pill, coil or HRT?
Just tell us at booking. Hormonal contraception and HRT affect some results, and our commentary will interpret your numbers in that context so they actually make sense for you.
What can an AMH test tell me?
AMH is the single best blood marker of your ovarian reserve, a useful indicator if you’re planning for a family, considering egg freezing, or simply want to understand your fertility. It can be tested on any day of your cycle.
When in my cycle should I take a hormone test?
It depends on the test. AMH can be done on any day. Baseline hormones (FSH, LH, oestradiol) are usually taken on days 2 to 5. Progesterone is taken around day 21 (about 7 days before your next period is due). We’ll guide you on timing when you book.
When is the best time to take a testosterone test?
Ideally in the morning (before 11am), when testosterone is at its natural peak. We’ll guide you on timing when you book.
What’s the best test if I think my testosterone is low?
Testosterone Plus, which measures total and free testosterone plus SHBG and the Free Androgen Index. Total testosterone alone misses many men whose symptoms come from low free testosterone, so getting the complete picture matters.
Do I need an allergy test or intolerance test?
If your reactions are fast (hives, swelling, wheezing), the 295-allergen IgE panel is the right starting point. If they’re slower and gut-based (bloating, cramps, fatigue), a targeted intolerance or coeliac profile may suit you better. Not sure? Call us and we’ll guide you.
What does the 295-allergen panel test for?
Foods, pollens, animals, dust mites, moulds, insect venoms, drugs and contact allergens (all from a single blood sample). The full allergen list can be found on the product page.
How accurate are home finger-prick tests compared to clinic tests?
Our home finger-prick tests use the same accredited laboratories as our clinic tests. While clinic tests allow for more comprehensive panels, home tests are highly accurate for the parameters they measure.
Do I need a GP referral for a blood test?
No, you don’t need a GP referral. You can book directly with us for any blood test. We are a private clinic offering direct access to comprehensive blood testing.
How old do I have to be to have a blood test?
We will only draw blood from those aged 16 and above due to legal requirements.
How long does it take for the blood test results to come?
If you have used our clinic to complete a blood test, we send off all samples the same day to the lab to be processed. If you have used a home test kit, then once your sample has been sent off the lab will analyse your sample. Results are usually received within 72 hours.
How do I perform the home finger-prick test?
Your home blood test kit will contain easy-to-follow instructions on how to take your own finger blood sample. If you have any concerns or questions prior to using the kit, please contact our phlebotomists who will be happy to assist.
How do I prepare for a blood test?
There is no preparation required prior to taking any of the blood tests. Please simply remember to stay hydrated prior to your appointment. This is to help your veins dilate better to enable a quick and efficient blood sample to be taken and reduce the risks of feeling faint following your blood test.
Please inform the phlebotomist before your test if you are currently taking any blood thinning medication.
Should I fast before my blood test?
Fasting is not required for most blood tests. However, if your profile includes cholesterol tests and you’ve previously had high levels, consider fasting for 8 hours beforehand. While not essential, fasting can provide more accurate results.
Note: Fasting means abstaining from any food and drink, except for water.