Weight Loss Management Advanced

Lipid Profile

Assesses cholesterol balance and cardiovascular risk, which are strongly influenced by weight and diet.

• Total Cholesterol

  Combined measure of all cholesterol types in the blood. Used alongside HDL, LDL, and triglycerides to evaluate cardiovascular risk.

• Low Density Lipoprotein (LDL) Cholesterol

  Often called “bad cholesterol”, elevated LDL contributes to plaque build-up in arteries and increases cardiovascular risk. A key marker to monitor during weight-loss treatment.

• High-Density Lipoprotein (HDL) Cholesterol

  Known as “good cholesterol”, HDL helps remove excess cholesterol from the bloodstream. Higher levels are protective against heart disease.

• HDL Percentage

  Calculates HDL as a proportion of total cholesterol. Useful for assessing the overall quality of the lipid profile alongside absolute values.

• Triglycerides

  A type of fat in the blood linked to diet, alcohol, and metabolic health. Elevated levels can indicate insulin resistance or cardiovascular risk.

Diabetes & Metabolic Health

Evaluates long-term blood sugar control - a core marker for anyone on a weight-loss programme.

• HbA1c (Glycosylated Haemoglobin)

  Reflects average blood glucose over the previous 2–3 months. Used to screen for pre-diabetes, diagnose diabetes, and monitor long-term metabolic control during weight loss.

Thyroid Function

• Thyroid Stimulating (TSH)

  A pituitary hormone that regulates thyroid activity. Abnormal levels can affect metabolism, weight, energy, and mood.

• Free T4 (Thyroxine)

  The active form of thyroid hormone available to tissues. Helps evaluate whether the thyroid is producing sufficient hormone to support healthy metabolism.

Liver Function

Checks liver health, protein status, and bile flow. Fatty liver is common in people carrying excess weight and should be monitored during treatment.

• Alanine Transaminase (ALT)

  A liver enzyme that is one of the most sensitive markers for liver cell damage. Often raised in non-alcoholic fatty liver disease (NAFLD), which is common in patients carrying excess weight.

• Aspartate Aminotransferase (AST)

  A liver and muscle enzyme. Elevated levels can indicate liver cell damage, fatty liver disease, or muscle injury.

• Gamma Glutamyl Transferase (GGT)

  A liver and bile duct enzyme. Useful for detecting bile flow problems, alcohol-related liver strain, and fatty liver.

• Alkaline Phosphatase (ALP)

  An enzyme found in the liver, bile ducts, and bone. Helps identify liver, gallbladder, or bone-related issues.

• Total Bilirubin

  A waste product from red blood cell breakdown processed by the liver. Elevated levels can indicate liver strain or bile flow issues.

• Albumin

  The main protein made by the liver. Reflects nutritional status, hydration, and liver function — all important during a weight-loss programme.

• Globulin

  A group of proteins involved in immune function and transport. Helps detect liver disease, chronic inflammation, or protein imbalances.

• Total Protein

  A combined measurement of albumin and globulin. Used to assess nutritional status, liver function, and fluid balance.

Kidney Function

Evaluates how well the kidneys are filtering waste and maintaining electrolyte balance - important for GLP-1 treatment safety.

• Creatinine

  A waste product filtered by the kidneys. Raised levels can indicate reduced kidney function, which is important to monitor before and during GLP-1 treatment.

• Urea

  A waste product from protein breakdown, filtered by the kidneys. Affected by hydration, diet, and kidney function.

• Estimated Glomerular Filtration Rate (eGFR)

  A calculated measure of how well the kidneys are filtering blood. One of the most important indicators of overall kidney health.

• Sodium

  An electrolyte critical for fluid balance, blood pressure, and nerve function. Can be affected by reduced appetite, vomiting, or dehydration during weight-loss treatment.

Pancreatic Markers

Monitors pancreatic health, which is routinely tracked in patients using GLP-1 medications such as Mounjaro® and Wegovy®.

• Lipase

  A pancreatic enzyme that digests fats. Raised levels can indicate pancreatic inflammation, which is a monitored side effect of GLP-1 medications such as Mounjaro and Wegovy.

• Amylase

  A pancreatic and salivary enzyme. Used alongside lipase to detect pancreatic inflammation or irritation during GLP-1 treatment.

Full Blood Count

Assesses overall blood health, immunity, and oxygen delivery. Helps identify anaemia and other conditions that can cause fatigue during a weight-loss programme.

• Haemoglobin

  The protein in red blood cells that carries oxygen. Low levels indicate anaemia, which can present as fatigue or breathlessness – symptoms that can overlap with weight-loss side effects.

• Haematocrit

  The proportion of blood made up of red blood cells. Used to assess anaemia, dehydration, or blood disorders.

• Red Cell Count

  The number of red blood cells in a given volume of blood. Helps detect anaemia or blood production issues.

• Mean Cell Volume (MCV)

  Measures the average size of red blood cells. Helps classify the type of anaemia – for example, iron deficiency vs B12/folate deficiency.

• Mean Cell Haemoglobin (MCH)

  The average amount of haemoglobin per red blood cell. Supports diagnosis of different types of anaemia.

• Mean Cell Haemoglobin Concentration (MCHC)

  The concentration of haemoglobin within red blood cells. Helps identify iron-deficiency and other anaemias.

• Red Cell Distribution Width (RDW)

  Measures variation in red blood cell size. Elevated RDW can be an early sign of nutritional deficiency.

• White Cell Count

  The total number of white blood cells. Used to detect infection, inflammation, and immune function changes.

• Neutrophils

  The most common white cell, important for fighting bacterial infection. Abnormal levels can reflect infection or inflammation.

• Lymphocytes

  White cells involved in viral immunity and long-term defence. Used to assess immune status.

• Monocytes

  White cells involved in chronic inflammation and tissue repair. Changes can indicate infection or systemic inflammation.

• Eosinophils

  White cells linked to allergic responses and parasitic infection. Elevated levels can point to allergy or inflammation.

• Basophils

  White cells involved in allergic and inflammatory responses. Rare but useful in identifying specific immune conditions.

• Platelet Count

  Cells responsible for blood clotting. Abnormal counts can indicate bleeding, clotting, or bone marrow issues.

• Mean Platelet Volume (MPV)

  The average size of platelets. Provides additional information about platelet production and cardiovascular risk.

Iron Status

Assesses iron availability and storage, essential for energy production and healthy red blood cells.

• Iron

  The amount of iron circulating in the blood. Essential for oxygen transport and energy production – deficiency can contribute to fatigue during weight loss.

• Total Iron-Binding Capacity (TIBC)

  Measures the blood’s capacity to bind iron to transferrin. Helps differentiate between types of iron deficiency and iron overload.

• Unsaturated Iron-Binding Capacity (UIBC)

  The remaining capacity of transferrin to bind more iron. Used alongside TIBC to evaluate iron metabolism.

• Transferrin Saturation

  Shows the percentage of transferrin currently carrying iron. A key indicator of iron availability in the body.

Vitamins

Measures Vitamin D and B12, two of the most common deficiencies that contribute to fatigue and affect weight-loss progress.

• Vitamin D (25-OH)

  Essential for bone health, immune function, and mood. Deficiency is common in the UK, particularly in people with excess weight, and may affect overall well-being during a weight-loss programme.

• Vitamin B12

  Important for red blood cell production, nerve function, and energy levels. Deficiency can cause fatigue, low mood, and tingling — symptoms that may overlap with weight-loss side effects.